"Herd immunity": a rough guide.
نویسندگان
چکیده
The term "herd immunity" is widely used but carries a variety of meanings. Some authors use it to describe the proportion immune among individuals in a population. Others use it with reference to a particular threshold proportion of immune individuals that should lead to a decline in incidence of infection. Still others use it to refer to a pattern of immunity that should protect a population from invasion of a new infection. A common implication of the term is that the risk of infection among susceptible individuals in a population is reduced by the presence and proximity of immune individuals (this is sometimes referred to as "indirect protection" or a "herd effect"). We provide brief historical, epidemiologic, theoretical, and pragmatic public health perspectives on this concept.
منابع مشابه
Population viscosity suppresses disease emergence by preserving local herd immunity.
Animal reservoirs for infectious diseases pose ongoing risks to human populations. In this theory of zoonoses, the introduction event that starts an epidemic is assumed to be independent of all preceding events. However, introductions are often concentrated in communities that bridge the ecological interfaces between reservoirs and the general population. In this paper, we explore how the risks...
متن کاملHerd Immunity/Herd Infection: Cultural Artifacts of Marginalization and the Dynamics of AIDS
We examine social conditions under which high prevalence of infectious disease can become endemic within a community, in effect constituting a state of ‘herd infection’ inverse to epidemiological herd immunity. For something like AIDS, under such a circumstance, a single behavioral lapse or adverse accident will probably be a death sentence.
متن کاملCRISPR-based herd immunity can limit phage epidemics in bacterial populations.
Herd immunity, a process in which resistant individuals limit the spread of a pathogen among susceptible hosts has been extensively studied in eukaryotes. Even though bacteria have evolved multiple immune systems against their phage pathogens, herd immunity in bacteria remains unexplored. Here we experimentally demonstrate that herd immunity arises during phage epidemics in structured and unstr...
متن کاملAssessing herd immunity against rubella in Japan: A retrospective seroepidemiological analysis of age-dependent transmission dynamics
متن کامل
Network structure can play a role in vaccination thresholds and herd immunity: a simulation using a network mathematical model.
To the Editor—Dominguez et al. [1] described outbreaks of measles occurring in Catalonia despite good vaccination rates. The way in which heterogeneity in the distribution of nonimmune individuals diminishes herd immunity can be explained using network simulation models. Herd immunity is the indirect impact of vaccination on an epidemic. This effect is caused by having a sufficient number of im...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
دوره 52 7 شماره
صفحات -
تاریخ انتشار 2011